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Cozac® rating

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Cozac®

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Cozac® is a psychiatric drug used for the treatment of major mental disorders, including depression, obsessive-compulsive disorder, and bulimia nervosa. Cozac® is only indicated for the management of aforementioned conditions in adults but can be taken by children and adolescents aged 8-18 years in case of moderate to severe depression. Read more

Other names for this medication:
Oxetin®, Psycotene®, Fluoxecare®, Flunil®, Cadflo®, Olena®, Oxactin®, Prozac®, Prozep®

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Active Ingredient:
Fluoxetine

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Description

Cozac® is manufactured by Consern Pharma. Cozac® contains an active constituent called Fluoxetine, an antidepressant belonging to a drug class selective serotonin reuptake inhibitors (SSRIs), also known as second-generation antidepressants.

Indications:

- major depressive disorder (MDD) (feeling sad, inability to sleep properly or to enjoy life as one used to);

- obsessive-compulsive disorder (OCD) (obsessive states with persistent ideas, that make patient do repetitive actions);

- bulimia nervosa (an eating disorder characterized by binge-eating and purging);

- panic disorder, with or without agoraphobia (excessive and persistent fear of public places or open areas);

- depressive episodes associated with Bipolar I Disorder (only in combination with another medication like Olanzapine);

- off-label treatment of premature ejaculation (PE), (or too early ejaculation within 1 minute after penetration).

MOA (mechanism of action):

Fluoxetine works by slowing the reabsorption of serotonin in the brain. Serotonin is a chemical neurotransmitter, which sends electrical impulses from one neuron to the next. Normally, serotonin is quickly reabsorbed, but Fluoxetine lets the serotonin remain in the synaptic gap between neurons for a longer period of time. This allows the chemical to send additional messages to the receiving neuron, which results in improvement in mood.

Dosage

Swallow a capsule whole with a drink of water.

Cozac® should only be used in children and adolescents aged between 8-18 years for the treatment of moderate to severe depression (alongside psychological therapy).

For depression and OCD: 20 mg once daily dose. The daily dose may be increased later if no clinical improvement is observed.

For bulimia: 20 mg three times daily.

For panic disorder: 10 mg/day. After one week increase the dose to 20 mg/day. The dose may be increased after several weeks if no clinical improvement is observed.

Take Cozac® at the same time each day.

Treatment in children should be held under the doctor's supervision.

Precautions:

Do not stop taking Cozac® after a week or two, feeling it doesn't work.

It can take up to 2 weeks after starting this treatment before positive effect appear, and 4-6 weeks before a patient feels the full benefit.

Be careful while taking Cozac® tablets if you have diabetes, as it may alter your blood glucose levels and your insulin/medication may need adjusting.

When stopping treatment with Cozac®, it is best to decrease the dose gradually over a period of several weeks or months to minimize the withdrawal reactions.

Avoid consuming alcohol while taking Cozac®.

Missing a dose

If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule. Do not take a double dose of Cozac® to compensate the missed dose.

Overdose

If you take an overdose of Cozac®, you should seek emergency medical attention or contact your healthcare provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cozac® are:

  • allergic reactions (wheeziness, difficulty in breathing or dizziness, swelling of the eyelids, face, lips or throat, rash, convulsions)
  • insomnia
  • dizziness
  • sleepiness
  • headache
  • diarrhea
  • feeling sick
  • dry mouth
  • fatigue
  • sore throat
  • depression
  • anxiety
  • agitation
  • nervousness
  • decreased sexual interest
  • teeth grinding
  • numbness and tingling
  • shaking
  • muscle tense
  • abnormal taste
  • lack of attention
  • visual disturbance
  • ringing in ears

Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Cozac® if you are allergic to Fluoxetine or any of the other ingredients in the tablets.

Do not take Cozac® if you are taking or have taken monoamine oxidase inhibitor drug (MAOI) (selegiline, moclobemide), or MAOI-like drug (linezolid) for depression.

Do not take Cozac® you are taking pimozide (drug for the treatment of mental disorders like schizophrenia or psychosis).

Do not take Cozac® if you suffer from epilepsy, have a history of seizures. or are receiving ECT (electroconvulsive therapy).

Do not take Cozac® if you suffer or have suffered from manic depressive illness (bipolar disorder) or schizophrenia.

Do not take Cozac® if you have suffered from a bleeding disorder or have been taking anticoagulants (e.g. acetylsalicylic acid, warfarin).

Do not take Cozac® if you have or have previously had thoughts of harming or killing yourself.

Do not take Cozac® if you have serotonin syndrome, low sodium levels in your blood, liver disease, have or have a history of angle-closure glaucoma.

Cozac® is only for use in adults (over 18 years of age). It can only be used to treat children and adolescents aged 8-18 years old with obsessive compulsive disorder (OCD).

Cozac® is not recommended for use if you are pregnant, likely to become pregnant or are breastfeeding until your doctor decides if this medication is right for you.

Do not drive or operate machinery while treatment with Cozac®.

Consult your doctor prior taking Cozac® if you are taking any of the following medications: amino acid tryptophan (for depression), diazepam (a sedative), lithium (for mania and depression), anesthetics (fentanyl), tricyclic antidepressants (imipramine), medications for schizophrenia and other mental disorders (perphenazine, levomepromazine, olanzapine), medications to treat diabetes (tolbutamide), cimetidine (for ulcers), non-steroidal anti-inflammatory drugs (NSAIDs), diuretics (water pills), medications to treat epilepsy (phenytoin, phenobarbital, carbamazepine), tramadol (a painkiller), sumatriptan (for migraine), fenfluramine (appetite suppressant), herbal remedy St. John’s Wort, drugs used to regulate the rate and rhythm of the heart (flecainide, propafenone, verapamil, diltiazem), drugs used to treat fungal infections (ketoconazole, itraconazole, posaconazole, voriconazole, fluconazole), drugs used to prevent nausea and vomiting after an operation or chemotherapy (aprepitant).

Q: What is Cozac®?

A: Cozac® is a psychiatric drug used for the treatment of major mental disorders, including depression, obsessive-compulsive disorder, and bulimia nervosa. Cozac® is only indicated for the management of aforementioned conditions in adults but can be taken by children and adolescents aged 8-18 years in case of moderate to severe depression.

Q: Does Cozac® cause dependence?

A: Cozac® is not addictive. However, sudden stopping or decrease in dose of Cozac® may cause withdrawal reactions like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, nausea, vomiting and shaking. Consult the doctor regarding the use of Cozac® and discontinuation.

Q: Is Cozac® a stimulant?

A: No, it isn't. Cozac® is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It does not stimulate the brain but improves depression by increasing the levels of a chemical called serotonin in the brain.

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